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KMID : 1201420180110020134
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Journal of Neurocritical Care
2018 Volume.11 No. 2 p.134 ~ p.136
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A Variant Guillain-Barre Syndrome with Anti-Ganglioside Complex Antibody
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Huh So-Young
Lee So-Young
Lee Jin-Hyung
Lee Won-Gu
Kim Jong-Kuk
Yoon Byeol-A
Kim Nam-Jun
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Abstract
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Background: Recently, anti-ganglioside complex (GSC) antibodies were discovered among the various subtypes of Guillain-Barre syndrome. GSC is the novel glycoepitopes formed by two individual ganglioside molecules.
Case Report: We present a 36-year-old man with overlap Miller Fisher syndrome and acute bulbar palsy who had anti-GSC antibody that provided diagnostic robustness.
Conclusion: Anti-GSC testing could be considered important in patients who show atypical manifestation with negative antibody reaction against each constituent ganglioside.
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KEYWORD
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Guillain-Barre syndrome, Miller Fisher syndrome, Antibodies, Gangliosides
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